I think it comes down to who you are as a person. Keep in mind I'm somewhat biased, but...
Jukepop basically pits you against other authors, so it's competitive, but there's a conflict of interest as well. If Jukepop rises in the public profile (ie. more good works), all of Jukepop benefits. The conflict, though, is that if you let the other guys pull ahead, then they're the ones who're going to be reaping the rewards, while you're basically stuck without a really good way to pull ahead or break away from the crowd (let alone monetize or any of that). For some personalities, that inherent competitiveness and competition, as well as being part of a community, it's good, and that's great. For some of us, though, that's anathema.
Another concern to watch out for would be the trend that some have reported here in the forums, where they say the Jukepop monetary rewards are less about how good your story is and more about how much you spam social media (Twitter update: "New post of X is up! Vote!" Facebook: "New post of X is up! Vote!"). Having good writing helps, I'm sure, and I'm sure you can pull ahead by pure writing merit alone, but this is the observed trend. If you're someone naturally adept with social media who would naturally be marketing yourself on this front anyways, then perhaps this is the route you want to go.
There's also a minor suspicion I have - knowing what little I know, and having observed Jukepop's methods, the only way I can really see them doing what they do & giving out the monetary rewards without going into the red is (noting how much they push signing up on facebook) that they're selling the regular browsers' information to organizations. It's only a suspicion, but I'm really not so fond of anything that integrates Facebook as much as they do.
It may be easier website building, but there are reviews (including mine) that bring up the fact that Jukepop is, as a generalized website for browsing serials, not that good an interface. I don't deduct stars, but I do mention how much I dislike it in reviews. I've seen two or three other people do the same.
Finally, returning to my first point, keep in mind that while Jukepop might help you get that initial audience, you may be limiting your potential growth by attaching yourself to Jukepop. My story is, I think, the runaway success of the past stretch. My readership has boomed, I have a crapton of reviews/ratings, and I've gone from getting five visitors a day to getting ten or twelve thousand (with thirty to sixty thousand views a day, even after the story has finished). All in the span of 2.5 years. To put it bluntly, while I might have signed on with Jukepop when I was younger, had lower expectations & didn't know everything I know now, I feel I wouldn't have achieved the same success if I was a part of the site, and I wouldn't have made the same money I'm now making.
I'm sorry I can't give you an impartial response, but those are my views. You really have to sit down and decide what your expectations are, and what your approach and goals are. Setting up a site isn't terribly hard (Wordpress makes it easy, selecting a theme, colors, and organizing the menus/pages with a very fluid interface), you'll get slower growth, but the growth will be wholly yours.
On my own experience can be found here: http://www.reddit.com/r/writing/comments/1tezu9/how_to_make_writing_fun_again/ce7jb6f if you want my general story. I talk about how I monetized there. I'm now considering, depending on how my next serial goes over the next few months, moving and subsisting entirely on the writing.